Gonadorelin (also referred to as Gonadorelin Acetate) is a synthetically produced gonadotropin-releasing hormone (GnRH). Gonadorelin primarily stimulates the synthesis and release of luteinizing hormone (LH) from the anterior pituitary gland. Follicle-stimulating hormone (FSH) production and release is also increased by gonadorelin, but to a lesser degree. In prepubertal females and some gonadal function disorders, the FSH response may be greater than the LH response.
Gonadorelin Peptide hormones
Product Description:
98%+ Purity Gonadorelin Raw Powder
Min order quantity: 10Vials Gonadorelin powder
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What is Gonadorelin?
Gonadorelin (also referred to as Gonadorelin Acetate) is a synthetically produced gonadotropin-releasing hormone (GnRH). Gonadorelin primarily stimulates the synthesis and release of luteinizing hormone (LH) from the anterior pituitary gland. Follicle-stimulating hormone (FSH) production and release is also increased by gonadorelin, but to a lesser degree. In prepubertal females and some gonadal function disorders, the FSH response may be greater than the LH response.
Gonadorelin Specification:
Complete certificate of analysis (COA) issued after every finished batch as follows:
Product Name | Gonadorelin Acetate | CAS No. | 34973-08-5 |
Molecular Formula | C55H75N17O13 | Molecular Weight | 1182.3 |
Batch No. | P131180104 | Mfgr. Date | Jan.28th, 2018 |
Quantity | 100 g | Exp. Date | Jan.27th, 2020 |
【Test】 | 【Specifications】 | 【Results】 | |
Appearance | White to off-White powder | Visual inspection | |
Light absorption | 0.55 to 0.61 | Conforms | |
Identification, TLC | Corresponds to reference standard | Conforms | |
Molecular Ion Mass | 1182.3±1 | 1182 | |
Specific optical rotation | -54 to -66 | -62 | |
Purity (HPLC): | NLT 98.0 % | 99.1% | |
Related Substances(HPLC) | Total impurities <2.0% | 0.9% | |
Acetic acid (HPLC) | 8.0 % to 12.5% | 10.2% | |
Water Content(Karl Fischer): | ≦7 % | 4.5% | |
Trifluoroacetic acid | ≦0.25% | 0.03% | |
Acetonitrile | ≦0.041% | 0.03% | |
Assay | 95.0~102.0% | Conforms | |
Bacterial Endotoxins: | ≦70IU/mg | Conforms | |
Long-term Storage | -20±5℃, protected from light |
Gonadorelin application:
For evaluating the functional capacity and response of the gonadotropes of the anterior pituitary also for evaluating residual gonadotropic function of the pituitary following removal of a pituitary tumor by surgery and/or irradiation.
Gonadorelin is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary. The pulsatility of GnRH secretion has been seen in all vertebrates, and it is necessary to ensure a correct reproductive function. Thus a single hormone, GnRH, controls a complex process of follicular growth, ovulation, and corpus luteum maintenance in the female, and spermatogenesis in the male. Its short half life requires infusion pumps for its clinical use.
Production facility:
The factory has GMP guideline plant which is compliant with ISO9001:2008, with extremely strict production and quality system, dedicated to provide high quality steroid products.