Loyal Biotechnology Co.,Ltd

Buserelin Peptide Hormones

Buserelin stimulates the pituitary gland's gonadotrophin-releasing hormone receptor (GnRHR). Buserelin desensitizes the GnRH receptor, reducing the amount of gonadotropin. In males, this results in a reduction in the synthesis and release of testosterone. In females, estrogen secretion is inhibited. While initially, there is a rise in FSH and LH levels, chronic administration of Buserelin results in a sustained suppression of these hormones.

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Product Details

Buserelin Peptide hormones

Product Description: 

98%+ Purity Buserelin Raw Powder

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  • Min order quantity: 10vials Buserelin powder

  • Pacakge: Discreet parcel

  • Delivery method: DHL,FedEx,UPS,TNT,EMS,HKEMS

  • Payment terms: Western Union, MoneyGram, Bank transfer, Bitcoin

  • Our Service:

    Over 99% custom pass, delivery time within 5~10days.

    Resend free product if the cargo was seized.

    Quality guarantee system based on GMP guideline and ISO9001:2008

 

Buserelin Specification:

Complete certificate of analysis (COA) issued after every finished batch as follows:

Product Name

Buserelin Acetate

CAS No.

68630-75-1

Molecular Formula

C60H86N16O13

Molecular Weight

1239.42

Batch No.

P132180201

Mfgr. Date

Feb.9th, 2018

Quantity

200 g

Exp. Date

Feb.8th, 2020

Test

Specifications

Results

Appearance

White to off-white powder

Conforms

Identification By HPLC

Retention time is same with the reference substance

Conforms

Specific optical rotation

-49°~-58°

-52°

Molecular Ion Mass

1239.4±1

Conforms

Amino Acid Composition

±10%

Conforms

Purity (HPLC) :

≥ 98%

99.59%

Related Substances(HPLC)

Total impurities <2.0%
Maximum single impurity: <1.0%

0.41%
0.14%

Acetic acid (HPLC)

3.0% to 7.0%

6.6%

Water Content(Karl Fischer) :

≦4.0 %

3.6%

PeptideContent:

NLT 80%

88.4%

Residual Solvents(Acetonitrile)

≦0.041%

Conforms

Assay(ByAnhydrous,
AceticAcid-free)

95.0~105.0%

101%

Bacterial Endotoxins:

≦55.5IU/mg

Conforms

Long-term Storage

-20±5℃, protected from light


Buserelin application:

Buserelin stimulates the pituitary gland's gonadotrophin-releasing hormone receptor (GnRHR). Buserelin desensitizes the GnRH receptor, reducing the amount of gonadotropin. In males, this results in a reduction in the synthesis and release of testosterone. In females, estrogen secretion is inhibited. While initially, there is a rise in FSH and LH levels, chronic administration of Buserelin results in a sustained suppression of these hormones.

For medicine use, Buserelin is approved for the treatment of hormone-responsive cancers including prostate cancer and premenopausal breast cancer, sex hormone-dependent uterine diseases including endometrial hyperplasia, endometriosis, and uterine fibroids, and in assisted reproduction for female infertility.It is also used off-label for the treatment of precocious puberty, as a puberty blocker in transgender children, and as a component of transgender hormone therapy. In ovulation induction, buserelin is used for pituitary suppression as an adjunct to gonadotropin administration. It has also been assessed as a nasal spray for use as a hormonal contraceptive in women, with a 96% anovulation rate.


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Production facility:

The factory has GMP guideline plant which is compliant with ISO9001:2008, with extremely strict production and quality system, dedicated to provide high quality steroid products.

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